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Symptoms of dementia that may be treated include but are not limited to: memory loss, difficulty communicating, difficulty with complex tasks, difficulty with planning and organizing, difficulty with coordination and motor functions, problems with disorientation (such as getting lost), personality changes, inability to reason, inappropriate behavior, paranoia, agitation, hallucinations, etc
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Of note, CD40 is a transmembrane glycoprotein surface receptor, a member of the TNF receptor superfamily, and its activation is associated with increased effectiveness of antigen presentation and the upregulation of major histocompatibility complex class II and costimulatory molecules CD80/CD86